First-trimester maternal serum pregnancy-associated plasma protein-A and pre-eclampsia
نویسندگان
چکیده
منابع مشابه
First-trimester maternal serum pregnancy-associated plasma protein-A and pre-eclampsia.
OBJECTIVES To examine the relationship between low maternal serum pregnancy-associated plasma protein-A (PAPP-A) and uterine artery pulsatility index (UtA-PI) at 11+0 to 13+6 weeks with subsequent development of pre-eclampsia (PE). METHODS UtA-PI and serum PAPP-A were measured in women attending for routine care at 11+0 to 13+6 weeks of gestation. In the population, 156 (1.9%) women developed...
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BACKGROUND Pregnancy-associated plasma protein-A (PAPP-A) is produced by the embryo and placenta during pregnancy, and its maternal serum concentrations are related to subsequent fetal growth. Evidence from animal models and in vitro experiments suggests that PAPP-A is particularly involved in the regulation of bone development. The aim of this study was to assess the correlation between late f...
متن کاملFirst-trimester maternal serum tumor necrosis factor receptor-1 and pre-eclampsia.
OBJECTIVES To examine whether the maternal serum concentration of the soluble receptor-1 of tumor necrosis factor-alpha (TNF-R1) at 11-13 weeks of gestation in pregnancies that subsequently develop pre-eclampsia is different from that in women without this complication. METHODS The concentration of TNF-R1 at 11 + 0 to 13 + 6 weeks was measured in samples from 128 cases that subsequently devel...
متن کاملFirst trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women with a priori high risk.
OBJECTIVE To evaluate whether first trimester maternal serum PP13 can predict pre-eclampsia among women with a priori high risk. METHOD This was a nested case-control study. Women less than 14 weeks' gestation at increased risk of developing pre-eclampsia were recruited. Venous blood samples were assayed for PP13 using enzyme-linked immunosorbent assay. PP13 multiples of median (MoM) were cal...
متن کاملMaternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsia.
OBJECTIVE To evaluate whether measurement of maternal serum inhibin-A and activin-A at 11 + 0 to 13 + 6 weeks of gestation, alone or in combination with second-trimester uterine artery pulsatility measured by Doppler velocimetry, is useful in predicting those women who will develop pre-eclampsia. METHODS This was a nested case-control study of pre-eclampsia cases with controls matched for ges...
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ژورنال
عنوان ژورنال: Ultrasound in Obstetrics and Gynecology
سال: 2009
ISSN: 0960-7692,1469-0705
DOI: 10.1002/uog.6280